San Francisco 49ers defensive lineman Keion White is taking Monday's matchup against Indianapolis Colts quarterback Philip Rivers very seriously.

The San Francisco 49ers defense has been surviving despite injuries, and a lot of that credit has been given to Robert Saleh. Saleh was always expected to use the 49ers as a pit stop to regain his strong reputation as a head coaching candidate and parlay this into a new job.

San Francisco 49ers wide receiver Ricky Pearsall has missed the team's first practice of the week due to knee and ankle injuries.

Despite an "admirable" showing by Philip Rivers in Week 15, Mike Florio and Chris Simms believe the 49ers offense will continue to roll against the Colts on Monday Night Football.

The NFL season continues in Week 15 when the San Francisco 49ers host the Tennessee Titans on Sunday. Start time, how to watch, stream and NFL TV schedule.

San Francisco 49ers fans remember how dire the club's quarterback situation was throughout the 2022 NFL campaign. First, it was Trey Lance, then Jimmy Garoppolo, the rise of Brock Purdy and a brief cameo from the ghost of veteran journeyman Josh Johnson.

The Indianapolis Colts and San Francisco 49ers understand the stakes Monday night. Both teams find themselves in the throes of tight division races where one more loss could eliminate them.

The 49ers' playoff picture has some options. But the 49ers' dream playoff scenario could include the 1 seed in the NFC.