AlphaFold An artificial intelligence system developed by Google DeepMind that predicts three-dimensional protein structures from amino acid sequences and, in AlphaFold 3, models biomolecular complexes ...

Slime mould Dictyostelium discoideum protein complex Q55DI5 (AF-0000000066503175), annotated as a transcription elongation factor. The single chain looked disordered, but modelling the homodimer ...

AlphaFold arrived as a technical moonshot that suddenly made protein structures feel like software rather than secrets of nature, and five years on it has rewired how laboratories plan experiments, ...

Inverse protein folding, the process of designing sequences that fold into a specific 3D structure, is crucial in bio-engineering and drug discovery. Traditional methods rely on experimentally ...

The tectonic shift that has occurred in structural and molecular biology thanks to the abundance of high-quality protein 3D structure models calls for a new outlook on protein structures as a source ...

A three-decade-old competition that has spawned three Nobel laureates is becoming victim to the chaos at the National Institutes of Health. The Community Wide Experiment on the Critical Assessment of ...

Nobel Prize in Chemistry 2024 co-laureate US chemist and computer scientist John Jumper gives his Nobel Prize lecture in Aula Magna, Stockholm University, Sweden, on December 8, 2024. Pontus ...

Intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging. Although ...

Scientists at St. Jude Children's Research Hospital have created a database that provides updated predicted structures on a regular basis, ensuring scientists can work with the most current ...

John Jumper, the Nobel Prize-winning researcher who led the AlphaFold project at Google DeepMind, is leaving the lab to join ...