Recently, photoredox catalysis has emerged as an appealing coupling partner for transition metal catalysis, termed metallaphotocatalysis, to develop new synthetic methodologies as well as improve the ...

Negishi cross-coupling reactions have been widely used to form C-C bonds since the 1970s and are often perceived as the result of two metals, zinc and palladium/nickel, working in synergy. But like ...

Using directed evolution, researchers have developed an enzyme that catalyses the formation of biaryl bonds (Nature 2022, DOI: 10.1038/s41586-021-04365-7). This new enzyme makes carbon-carbon bonds ...

Researchers have created and characterized a novel, three-component cross-coupling reaction that is a 'tremendous leap forward' in developing effective and practical iron-based reactions that could be ...

Scientists have developed a rapid, efficient protocol for cross-coupling reactions, vastly expanding the pool of chemicals that can be used for the synthesis of useful organic compounds. Scientists ...

Chemists are amped up about two new reactions that use electricity to form different types of carbon-carbon bonds. One transformation builds sp 3-sp 3 C–C bonds and the other creates sp 2-sp 3 C–C ...

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine. Normally, creating better ...

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According to a study published in Nature Communications, a research team led by Associate Professor Jiong Lu from the Department of Chemistry at the National University of Singapore devised an ...