Failure of chromosomal organization within human egg and sperm cells result in miscarriages and infertility. However, the mechanisms controlling these processes are not understood. The discovery of a ...

For reproduction to be successful, an egg cell must divide perfectly. Egg cell divisions are so error-prone, however, that they are the leading cause of miscarriages and birth defects in humans. In a ...

Embryo development starts when a single egg cell is fertilized and starts dividing continuously. Initially a chaotic cluster, it gradually evolves into a highly organized structure. Scientists have ...

Researchers have uncovered how egg cells prepare for the creation of life. Their work reveals the secrets of the Balbiani body, a remarkable structure that organizes essential molecules to guide early ...

A Northwestern Medicine study has shed light on one of the most intricate construction projects in biology: how cells build and coordinate the internal scaffolding needed to create a healthy egg. The ...

To understand why egg cells are more susceptible to errors, Wignall studies a football-shaped structure, called the spindle, which organizes genetic material before the egg divides. "The spindle is ...