The 24.8% relative risk reduction in prostate cancer seen in the finasteride arm prompted the early termination of the study on February 21, 2003, 15 months before its anticipated completion. While ...
A previous study showed that using 5-ARIs to treat benign prostate hyperplasia decreased the risk of low-grade PCa. Using 5α-reductase inhibitors (5-ARIs) to treat patients with lower urinary tract ...
The PCPT has shown finasteride to be an effective chemopreventive agent in low-grade prostate cancer. Enthusiasm for its widespread use has been tempered by the reported increase in high-grade cancers ...