A new human study has uncovered how the body naturally turns off inflammation. Researchers found that fat-derived molecules called epoxy-oxylipins rein in immune cells that can otherwise drive chronic ...

A research team has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery deepens the understanding of a new type of ...

Interleukin-10 (IL-10) is an anti-inflammatory protein that crucially controls intestinal immunity. Children with genetic defects in IL-10, or its receptors, suffer from a severe form of inflammatory ...

Phase 1b translational data demonstrate localized ileocolonic target engagement, suppression of inflammatory and fibrotic gene programs, and ...

The inflammatory response is a vital protective process, yet its dysregulation can lead to chronic conditions and tissue damage. Central to these processes is the regulation of nitric oxide (NO), a ...

Chronic inflammation is acknowledged as the fundamental cause of various pathological conditions, and in recent decades, there has been a growing focus on ...

An inflammatory sugar molecule produced by certain gut bacteria may play a key role in driving ALS, a study found.

Black ginseng extract (4 μg/mL) could inhibit the expression of MMP-1 in human foreskin fibroblasts damaged by inflammation. Additionally, 0.1% BGE could not only inhibit the secretion of PGE2 in a ...

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites. During a parasitic infection, specific immune cells ...