Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...

BIN1, a late-onset Alzheimer’s disease (LOAD) genetic risk factor, is involved in many cellular phenomena, including vesicular trafficking and tau production. Now, in the August 26 Cell Reports, ...

Synapses in the forebrain were thought of as purely GABAergic, yet they contain minute numbers of glycine receptors, often in the single digits.

Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers investigated how a ...

The latticework of extracellular protein that surrounds brain cells forms a particularly dense mesh around fast-spiking interneurons. Why do these cells need such thick coats? In the July 17 Nature ...

A researcher has developed a new model that provides a holistic view on how our brain manages to learn quickly and forms stable, long-lasting memories. Their study sheds light on the crucial role of ...

What are the three modes of neurotransmission, and how do they differ in terms of temporal coupling with action potentials? There are three modes of neurotransmission: stimulation-dependent release ...

According to a Mayo Clinic study published in Nature Neuroscience, the cells that act as the central nervous system's first line of defense against harm also play a role in helping the brain awaken ...

The way the brain develops can shape us throughout our lives, so neuroscientists are intensely curious about how it happens. A new study by researchers in The Picower Institute for Learning and Memory ...