Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease.
Spliceosomal introns are a defining feature of eukaryotic life; they are present in all known eukaryotic genomes and absent from all known non-eukaryotic genomes 1,2. Introns and splicing can have ...
Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global population infected with Mycobacterium tuberculosis. While most infections ...