Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell--sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet ...
(A) Schematic representation of the CRISPR-Cas9-mediated knockout of DNMT3B (DNMT3B KO) in M07e cells. The U6 promoter drives expression of an hDNMT3B-targeting single-guide RNA (sgRNA), while an EFS ...