The proper use of spike-in normalization in ChIP-seq improves sensitivity for detecting genome-wide changes between conditions, but improper use is common, calling some biological conclusions into ...

When normalizing data structures, attributes congregate around the business keys that identify the grain at which those attributes derive their values. Attributes directly related to a person, ...

We collected a unique pair of microRNA sequencing data sets for the same set of tumor samples; one data set was collected with and the other without uniform handling and balanced design. The former ...