How can a mutation in one single gene cause a disease with a wide range of symptoms? This situation is referred to as pleiotropy, and it has been identified in a wide range of species, even humans.

How does environmental complexity affect the evolution of single genes? Here, we measured the effects of a set of Bacillus subtilis glutamate dehydrogenase mutants across 19 different ...

Graduate student Reese Martin and his doctoral advisor, Ann Tate, assistant professor of biological sciences, used theoretical modeling to identify a potential relationship between genetic pleiotropy ...

Many of us probably remember the punnett squares by which we were introduced to the idea of genetic inheritance in school: a dominant allele in each of my brown-eyed parents hides a recessive allele ...

Pleiotropy poses a challenge for crop improvement because selecting for one beneficial trait can negatively impact another. In addition to Eveland’s research team, scientists from the University of ...