Neurodegenerative disease profoundly affects structures and pathways responsible for memory, cognition, and higher-order ...

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

It has been known for nearly 20 years that slow, synchronous electrical waves in the brain during deep sleep support the formation of memories. Why that is was previously unknown. Now, a team of ...

When Aβ aggregates stoke synaptic fires, tau tangles put them out. This phenomenon, demonstrated in animal models, now gains support in a human study, published September 18 in Nature Neuroscience.

Gamma brain waves are rhythmic electric processes in nerve cells called neurons. Nerve activity in the brain allows for communication throughout the brain to carry out functions such as memory, ...

A wave of recent neuroscience research has identified specific molecular and cellular mechanisms through which alcohol disrupts signaling between brain cells, offering a sharper picture of how ...