The definition is tricky, but the effects of poor metabolic health are clear — and can wreak havoc on the body. By Nina Agrawal “Metabolic health” is a wellness catchphrase that is hard to escape.

A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life. Each of us starts ...

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in ...

Researchers have identified small molecules in the blood that may impact early childhood development, showing how dietary exposures, early life experiences, and gut health can influence a child's ...

Drug metabolism is a central factor in drug discovery and development, impacting safety, pharmacokinetics, and pharmacodynamics. Research into drugs’ in vitro metabolism in human and animal tissues ...

Lysosomes were once viewed mainly as cellular waste disposers, but are now recognized as key hubs for nutrient sensing and ...

Something happens when a rat starts running. Not just the obvious things, the faster heart, the warming muscles, the rhythmic percussion of paws against the wheel. Something quieter. Something that ...

Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ...