Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

CCN5 reduced cardiac cellular senescence in preclinical models of cardiovascular disease. Learn how this could shape ...

Cellular senescence—an irreversible cell-cycle arrest coupled with the production of pro-inflammatory secretions known as SASP—is now viewed as a central driver of musculoskeletal aging. Accumulation ...

Scientists have identified prematurely aged astrocytes in the brains of Alzheimer’s patients, particularly those with the APOE4 risk gene. Their findings suggest that cellular senescence in these ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...

A study in mice suggests that senescent cells are at least partially responsible for post-surgical delirium and similar conditions in elderly people—and identifies a combination of drugs that might be ...

UConn Center on Aging researchers have published a new editorial in the journal Aging titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?" In ...

Senescent cells, which are damaged and inflammatory, contribute significantly to aging. Researchers at the Max Planck Institute for Biology of Aging have found that worms can enter a senescent-like ...

Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 ...

A new research paper was published in Volume 18 of Aging-US on February 10, 2026, titled "Aging-associated mitochondrial ...