RMD Open

Dental infection is associated with early relapse in patients with ANCA-associated vasculitis

Objectives Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic autoimmune disease where infections ...
RMD Open

Salvage therapy with JAK inhibitors in refractory Takayasu arteritis: a multicentre experience

Takayasu arteritis (TAK) remains a therapeutic challenge, and some patients develop refractory disease despite conventional ...
rmdopen.bmj

Real-world effectiveness of b/tsDMARD switching in low-inflammatory difficult-to-treat rheumatoid arthritis: insights from the FIRST registry

Objectives To assess the effectiveness of switching biological or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in patients with low-inflammatory difficult-to-treat rheumatoid ...
rmdopen.bmj

Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a ...

Objectives To evaluate the potential of clinical factors, ultrasound findings, serum autoantibodies, and serum cytokine and chemokine profiles as predictors of clinical outcomes in rheumatoid ...
rmdopen.bmj

Long-term safety of bimekizumab in adult patients with axial spondyloarthritis or psoriatic arthritis: pooled results from integrated phase IIb/III clinical studies

Objective To assess the long-term safety profile of bimekizumab (BKZ) in patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). Methods Safety data pooled from six integrated ...
rmdopen.bmj

Clusters in paediatric Behçet’s disease: a multicentre international study

Objectives Clinical features of Behçet’s disease (BD) exhibit significant variability, not only from patient to patient but also according to gender and geographical region. This study aims to ...
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Frailty in rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis ...

Objective To assess the prevalence of frailty in rheumatoid arthritis (RA) and its association with baseline and longitudinal disease activity, all-cause mortality and hospitalisation. Participants ...
rmdopen.bmj

Inflammation, bone loss and fracture risk in spondyloarthritis

Osteoporosis (ie, low bone mineral density) is common in ankylosing spondylitis, related to both systemic inflammation and decreased mobility. Vertebral fracture risk is increased; acute back pain in ...
rmdopen.bmj

Autoantibodies as predictors of progression to rheumatoid arthritis: a systematic review and meta-analysis

Background The aim of this systematic review and meta-analysis was to examine autoantibody positive individuals and define: (a) the relative risk of rheumatoid arthritis (RA) compared with ...
rmdopen.bmj

Correction: Spotlight on Sjögren’s: a patient perspective on burden of illness and unmet needs – results from a real-world survey

Marvel J, Kenney G, Church J, et al. Spotlight on Sjögren’s: a patient perspective on burden of illness and unmet needs – results from a real-world survey. RMD Open 2026;12:e006166. This article has ...
rmdopen.bmj

Synovitis scoring in hand osteoarthritis with ultrasonography: the performance of the Global OMERACT/EULAR Ultrasound Synovitis Score (GLOESS) is comparable to synovial ...

Background Inflammation is increasingly recognised as a treatment target in hand osteoarthritis, and therefore correct measurement of local inflammation is essential. This study aimed to assess ...
rmdopen.bmj

Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus ...

Objectives To test the reliability of new ultrasound (US) definitions and quantification of synovial hypertrophy (SH) and power Doppler (PD) signal, separately and in combination, in a range of joints ...