Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these ...

The immune system provides an integral defense against cancer growth and progression. Activating an anti-tumor immune response relies on several biological steps that can ultimately result in the ...

When a cell divides, it performs a feat of microscopic choreography—duplicating its DNA and depositing it into two new cells.

At the 2024 annual meeting of the International Society for Cell & Gene Therapy (ISCT) in Vancouver, Canada, Hélio Tomás, PhD, senior research associate at the Instituto de Biologia Experimental e ...

A new study from Whitehead Institute Member Jonathan Weissman reveals how cells may activate a compensation system that can, in some cases, reduce the effects of potentially harmful genetic mutations.

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Every year, the media informs us that we’re on the cusp of the golden age of something. While the expected trend often comes to fruition, it’s rarely as smooth a process as advertised. Drug discovery ...

This hybrid system lets researchers zoom in on living human cells with incredible detail. This offers a new real time insight into how the flu virus operates. For the first time, researchers could ...

Emily Whitehead made the history books in 2012 when she become the first pediatric patient with B-cell acute lymphoblastic leukemia to be given a chimeric antigen receptor (CAR) T-cell therapy. After ...